Kuyanika kuzizira, komwe kumadziwikanso kuti kuumitsa-kuzizira, ndi njira yochepetsera madzi m'thupi yomwe imagwiritsidwa ntchito pochiza zinthu zomwe sizimva kutentha. Ukadaulowu tsopano ndiwokhazikika m'makampani ambiri opanga mankhwala. Chifukwa mokoma Dries Dries mankhwala popanda kuwononga kwachilengedwenso ntchito ndi thupi katundu.
一, mbiri yamakina akumawuma aunika zamankhwala
Mu 1906, Jacques-Arsene de Assonval anatulukira njira yowumitsa madzi oziziritsa kukhosi ku College de France ku Paris. Pambuyo pake, mkati mwa Nkhondo Yadziko II, idagwiritsidwa ntchito kwambiri kusunga seramu. Kuyambira nthawi imeneyo, kuyanika kozizira kwakhala njira imodzi yofunika kwambiri yosungiramo mankhwala osamva kutentha ndi zinthu zachilengedwe.
二, ubwino wa mankhwala amaundana-kuyanika makina
1, sungani mankhwala ndi zinthu zakuthupi
Mosiyana ndi njira zowumitsa kutentha, kuyanika-kuzizira kumagwiritsa ntchito kutentha kochepa komanso njira yotchedwa sublimation ndi desorption kuti madzi asungunuke. Zimapewa kutentha kwakukulu kuti ziteteze kukhulupirika kwa mankhwala, zomwe sizimakhudza mankhwala kapena thupi.
2. Sungani zochitika zamoyo
Kwa makampani opanga mankhwala, kumene mankhwala ambiri ndi zitsanzo ndi zosalimba, zosakhazikika, komanso kutentha, njira yotetezerayi ndi yabwino. Nthawi zambiri kuumitsa kuzizira kumatsimikizira zochitika zamoyo> 90%.
3, yosavuta kusunga ndi kunyamula
Chinyezi cha mankhwala owumitsidwa owumitsidwa ndi <3%, chomwe chili choyenera kusungidwa kwa nthawi yaitali ndi kunyamula kutentha. Ingowonjezerani madzi kuti mubwezeretse mankhwalawo ku chikhalidwe chake choyambirira. Kutha kukhazikika kwazinthu ndikuwonjezera moyo wa alumali wamankhwala ndi mankhwala kwapangitsa kuumitsa kuzizira kukhala imodzi mwa njira zomwe zimagwiritsidwa ntchito kwambiri pamakampani opanga mankhwala. Nthawi ya alumali ya zouma zowumitsidwa akuti ndi zaka 5 mpaka zaka 30.
三, kugwiritsidwa ntchito kofala kwa makina owumitsa owumitsa azachipatala
1. Mankhwala ufa
jakisoni: glycyrrhizin wowumitsidwa, recombinant human interferon γ, etc.
Tsinde cell, biopharmaceutical, mankhwala mankhwala;
b: Katemera: encephalitis inactivated katemera, intradermal jekeseni wa BCG katemera, mumps moyo attenuated katemera, yellow fever moyo attenuated katemera, etc.
c: Mapuloteni: immunoglobulin, prothrombin complex human, fibrinogen yaumunthu, seramu ya njoka, seramu ya scorpion venom, Staphylococcus A mapuloteni oyera mankhwala, etc.;
d: Mankhwala ophera tizilombo toyambitsa matenda: antitoxin wowuma wa diphtheria, antitoxin wowumitsidwa wa kafumbata, ndi zina zotero;
2. Zida Zamankhwala zaku China (kumaliza)
a: Zomera: Ginseng, Notoginseng, American ginseng, Dendrobium, Scutellaria skullcap, Licorice, Radix salva, Wolfberry, safflower, honeysuckle, chrysanthemum, Ganoderma lucidum, ginger, Peony, peony, Rehmannia, yam (Huaishan, Astrachelus), Ginkgo Cinkgo , peel lalanje, Tremella tremella, Hawthorn, amonke zipatso, Gastrodia gastrodia, Tianshan Snow Lotus, etc.;
b: Zinyama: royal jelly, placenta, cordyceps, seahorse, ndulu ya chimbalangondo, nswala, magazi agwape, musk, ejiao, heparin sodium, etc.;
3. Zopangira
Tizilombo zopangira, nyama zopangira, mankhwala zopangira, anaikira m'zigawo mankhwala;
4. Kuzindikira reagent
Kuyesa kwachilengedwe: ma reagents oyezetsa madzi, ma reagents oyesa nthaka ndi zina zouma zouma;
Kuzindikira kuzindikira reagent, kuyendera kuzindikira reagent, biochemical kuzindikira reagent;
5, zitsanzo zamoyo, minofu yachilengedwe
Mwachitsanzo, kupanga zosiyanasiyana nyama ndi zomera toyesa, youma ndi kusunga khungu, cornea, fupa, msempha, mtima valavu ndi zina m'mphepete zimakhala za xenogeneic kapena homologous transplantation nyama, monga amaundana-zouma;
6. Tizilombo tating'onoting'ono ndi algae
Monga mabakiteriya osiyanasiyana, yisiti, michere, protozoa, algae yaying'ono ndi zina zosungika kwa nthawi yayitali, monga kuunika kowuma.
7, mankhwala kwachilengedwenso, mankhwala
Monga kuteteza tizilombo toyambitsa matenda, mankhwala ophera tizilombo toyambitsa matenda, tizilombo toyambitsa matenda ndi katemera;
四, njira yowumitsa mankhwala
Kwenikweni, mankhwala owumitsa-owuma amakhala ndi njira zitatu zazikulu: kuzizira, kuyanika koyamba, ndi kuyanika kwachiwiri, zomwe zimaphatikizapo:
Kuzizira: Madzi amaundana mwachangu kuti aletse kupanga makhiristo akulu omwe angawononge makoma a cell.
Kuyanika koyamba (sublimation): Iyi ndi gawo lachiwiri la kuyanika kozizira, komwe kuthamanga kumachepetsedwa ndipo kutentha kumapangitsa kuti madzi oundana asungunuke. Kutengera chitsanzo, njirayi imatha kutenga paliponse kuyambira maola angapo mpaka masiku angapo kuti ithe. Mukamaliza kuyanika koyambirira, 93-95% ya madzi atuluka.
Kuyanika kwachiwiri (adsorption): Iyi ndi gawo lomaliza pomwe kutentha kumakwezedwanso kuchotsa chinyezi chotsalira. Madzi otsala omwe atsekeredwa mu matrix olimba amawotchedwa powonjezera kutentha.
Mankhwala owumitsidwa owumitsidwawo amaikidwa mu mbale zagalasi zokhala ndi zoyimitsa mphira ndi zisoti za aluminiyamu.
五. Mankhwala oyenera amaundana-kuyanika
Zitsanzo za mankhwala oziziritsa ndi:
katemera.
antibody.
erythrocyte
plasma
mahomoni
mabakiteriya
A virus.
enzyme
ma probiotics
Mavitamini ndi mchere
Collagen peptide
electrolyte
Yogwira mankhwala pophika
六, mankhwala amaundana chowumitsira analimbikitsa
Chowumitsira chowumitsira choyesera
Woyendetsa amawumitsa amaundana
Biological freeze-dryer
Monga katswiri wopanga makina owumitsa amawumitsidwa ndi mayankho, "ZOWIRI" Chidacho chili ndi chidziwitso chochuluka mu R & D ndikupanga.Chowumitsira amaundana choyesera, chowumitsira oyendetsa ndegendibiological freeze-dryeropangidwa ndi "BOTH" amatha kukwaniritsa zosowa za zitsanzo zazing'ono, zoyendetsa ndege kapena zazikulu, ngati mukufuna, chondeLumikizanani nafe, ndife okondwa kukupatsani zokambirana ndikuyankha mafunso aliwonse omwe muli nawo. Gulu lathu lidzasangalala kukutumikirani. Ndikuyembekezera kuyankhulana ndi kugwirizana nanu! "
Nthawi yotumiza: Jan-12-2024