Momwe mungapangire ufa wouma wozizira wa lumbrokinase

Ⅰ.Kugwiritsa Ntchito Ukadaulo Wouma ndi Kuzizira Pokonzekera Ufa wa Fibrinolytic Enzyme Lyophilized Enzyme

Kuumitsa mufiriji, komwe kumadziwikanso kuti lyophilization, ndi njira yochotsera chinyezi kuchokera ku zinthu pogwiritsa ntchito zida zowumitsira mufiriji kuti zisunge kapangidwe kake ndi magwiridwe antchito ake. Kukonzekera ufa wopangidwa ndi lyophilized enzyme ya earthworm fibrinolytic kumaphatikizapo magawo awiri akuluakulu: kuumitsa mufiriji ndi vacuum cleaner. Njirayi imachotsa chinyezi kuchokera ku enzyme extract pamene ikusunga ntchito yake yachilengedwe komanso kukhazikika.

Ⅱ.Kulima Mitundu Yabwino Kwambiri

Kusankha mitundu yobala zipatso zambiri kuti ipange ma enzyme ndikofunikira kwambiri kuti njira yopangira zinthu ipambane. Kudzera mu kuyesa ndi kukonza, mitundu yokhala ndi ntchito zambiri komanso yobala zipatso imakulitsidwa kuti iwonjezere mphamvu yopangira ma enzyme.

Ⅲ.Kuchotsa ndi Kuyeretsa

Ukadaulo wapamwamba wochotsa zinthu umagwiritsidwa ntchito kuti utulutse enzyme ya fibrinolytic ya nyongolotsi kuchokera ku mitundu ina ya tizilombo, kenako n’kuyeretsa kuti zichotsedwe. Njira zodziwika bwino zimaphatikizapo kusokoneza kwa ultrasound, centrifugation, ndi column chromatography, zomwe zimapangitsa kuti enzyme yoyera kwambiri ichotsedwe.

Ⅳ.Njira Yowumitsa Yozizira

Kugwiritsa ntchito"ZONSE ZIWIRI"FreezeDryerPogwiritsa ntchito zipangizo, chotsitsa cha enzyme chimakonzedwa kukhala ufa wokhazikika wa lyophilized. Panthawi yowumitsa ndi kuzizira, magawo monga kutentha ndi kuchuluka kwa vacuum amasinthidwa kuti atsimikizire kuti ntchito ndi kukhazikika kwa enzyme zikusungidwa.

Ⅴ.Ubwino wa Ukadaulo wa Freeze-Dryer

Ukadaulo wa "zonse ziwiri" wozizira umapereka ubwino wotsatirawu pakukweza kukhazikika ndi kupezeka kwa ufa wopangidwa ndi lyophilized enzyme wa earthworm:

Ⅵ.Ukadaulo Wozizira Kwambiri

Ukadaulo watsopano wopangidwa wozizira wa -50°C umazizira mofulumira chotsitsa cha enzyme, kuletsa kupangika kwa makristalo ndi kusinthasintha kwa kutentha komwe kungasokoneze ntchito ya enzyme.

Ⅶ.Kuwongolera Kuuma Molondola

Chowumitsira chozizira cha "ZONSE" chili ndi njira yolondola yowongolera kuumitsa, zomwe zimathandiza kutentha (-50°C mpaka +45°C) ndi kusintha kwa vacuum (1–30 Pa) kutengera zomwe zimachitika. Izi zimatsimikizira kukhazikika kwa enzyme ndi ntchito yake powumitsa.

Ⅷ.Kusanthula kwa Zotsatira Zochepetsa LDL-C

Enzyme ya fibrinolytic ya nyongolotsi ya m'nyanja yomwe imagwiritsidwa ntchito ndi ukadaulo wa freeze-dryer imasungabe ntchito zambiri zamoyo. Mayeso azachipatala akuwonetsa kuti mphamvu yake yochepetsera LDL-C imaposa kwambiri mphamvu ya ma enzymes omwe amakonzedwa mwachizolowezi. Zinthu zazikulu ndi izi:

1. Kusungunuka KowonjezerekaUfa wosungunuka umasungunuka mwachangu m'madzi, kutulutsa zinthu zogwira ntchito ndikuwonjezera kuyamwa ndi kugwiritsidwa ntchito m'thupi.

2. Kusunga Zochita: Njira yowumitsa ndi kuzizira imachepetsa kuletsa kwa ma enzyme, zomwe zimapangitsa kuti igwire ntchito nthawi yayitali m'thupi ndikuwonjezera mphamvu yochepetsera LDL-C.

Kugwiritsa ntchito ukadaulo wowumitsa wozizira pokonza ufa wa fibrinolytic wa enzyme ya earthworm kumasunga ntchito ya enzyme ndi kukhazikika pamene kukuwongolera kupezeka kwa bioavailability. Izi zimapereka mankhwala othandiza kuchepetsa LDL-C ndikukweza thanzi la mitsempha yamagazi. Ndi kupita patsogolo kosalekeza muukadaulo wowumitsa wozizira, kugwiritsa ntchito kwambiri kwa "ZONSE" zowumitsa zozizira popanga ufa wa enzyme kumapereka njira zatsopano zopewera ndi kuchiza matenda amtima.

Ngati mukufuna kudziwa zambiri zaMakina Oumitsira Ozizirakapena muli ndi mafunso aliwonse, chonde musazengereze kuyankhaLumikizanani nafeMonga wopanga makina owumitsira makina oziziritsa, timapereka zinthu zosiyanasiyana, kuphatikizapo mitundu yapakhomo, ya labotale, yoyeserera, ndi yopangira. Kaya mukufuna zida zogwiritsidwa ntchito kunyumba kapena zamafakitale akuluakulu, tikhoza kukupatsani zinthu ndi ntchito zabwino kwambiri.